Results 201 to 210 of about 359,187 (310)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Analytical Chemistry for Environmental and Human Health. Development of a gas absorption microchip using porous glass and its evaluation for analytical applications.

, 2000
Takashi Korenaga, Tamao Odake, Yasunari Ono, Long Rong   +3 more
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Mitigating eutrophication may elevate neurotoxic mercury risks in global coastal ecosystems. [PDF]

Eco Environ Health
Kong X, Chen L, Yin Y, Cai Y, Li Y.
europepmc   +1 more source

Analytical Chemistry for Environmental and Human Health. Determination of aluminium in biological samples and drinking water by kinetic-differentiation mode HPLC with fluorescent detection.

, 2000
Makoto Sato, Jun Matsuda, Harunobu Murayama, Ryong‐Woon Shin, Emiko Kaneko, Takao Yotsuyanagi   +5 more
openalex   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

A dataset of chemical reaction pathways incorporating halogen chemistry. [PDF]

Sci Data
Lee M, Jeong J, Ashyrmamatov I, Ucaxk UV, Kim S, Lee J, Sim E.   +6 more
europepmc   +1 more source

Analytical Chemistry for Environmental and Human Health. Multielement determination and speciation of major-to-ultratrace elements in green tea leaves by ICP-AES and ICP-MS.

, 2000
Hirotaka Matsuura, Akiko Hokura, Hiroki Haraguchi   +2 more
openalex   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Physical activity and polluted air: implications for COPD prevention and policy. [PDF]

Lancet Reg Health West Pac
Hahad O, Keller K, Lelieveld J.
europepmc   +1 more source