Results 41 to 50 of about 1,441,968 (290)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Observations of nitryl chloride and modeling its source and effect on ozone in the planetary boundary layer of southern China [PDF]

, 2016
Nitryl chloride (ClNO2) plays potentially important roles in atmospheric chemistry, but its abundance and effect are not fully understood due to the small number of ambient observations of ClNO2 to date.
Blake, Donald R, Brown, Steven S, Dube, William P, Li, Qinyi, Louie, Peter KK, Luk, Connie WY, Poon, Steven CN, Tham, Yee Jun, Tsui, Wilson, Wang, Tao, Wang, Zhe, Xue, Likun, Zha, Qiaozhi   +12 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Challenges and opportunities in the selective degradation of organophosphorus herbicide glyphosate

iScience
Summary: The wide and continuous usage of glyphosate in the environment poses a serious threat to biological systems. Besides the accumulation of glyphosate in vivo, a growing body of research has revealed that aminomethylphosphonic acid (AMPA), the main
Lei Jin, Yingping Huang, Liqun Ye, Di Huang, Xiang Liu   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Incrementalism of environmental innovations versus paradigmatic change: A comparative study of the automotive and chemical industries [PDF]

Environmental innovations; technological regime; technological paradigm; environmental regulation; automotive industry; green ...
Maïder SAINT JEAN (GREThA), Vanessa OLTRA (GREThA)   +1 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Estado da arte da cromatografia gasosa de alta resolução e alta temperatura State of the art of high temperature high resolution gas chromatography

Química Nova, 2000
The developments in stationary phase synthesis and capillary column technology, have opened new perspectives in analysis of high molecular mass compounds (³600 daltons) and thermolabile organic compounds by High Temperature High Resolution Gas ...
Alberto dos Santos Pereira, Francisco Radler de Aquino Neto   +1 more
doaj   +1 more source

R. M. Harrison and S. J. De Mora: Introductory Chemistry for the Environmental Sciences [book review] [PDF]

, 2000
Harrison and De Mora have revised the first edition of their book, Introductory Chemistry for the Environmental Sciences, which has an intended reading audience of college or university undergraduates who are studying or majoring in the environmental ...
Hoffmann, Michael R.
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