Results 121 to 130 of about 8,693,539 (346)
Customers as decision-makers: strategic environmental assessment in the private sector [PDF]
Despite its diversification and global spread, strategic environmental assessment (SEA) remains limited mainly to activities characterised by well-defined planning processes, typically within the public sector.
Byron H. +31 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Impact of Green Practices on Buying Habits in Pakistan’s Food Sector
The review intends to research the green advertising practices and its consequences for the client’s image inclination in sustenance segment of Pakistan.
Jafar Rana Adeel +2 more
doaj +1 more source
Environmental pollution, increasing damages in the nature and deformation of ecosytem have started to worry consumers and the environemental concern has formed in time.
E. Onurlubas
semanticscholar +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Environmental Concern Fuels Consumer Activism around the World
Consumer activism is one of the most impactful movements of our time. It involves citizens participating in changing human living patterns, particularly those related to production and consumption.
Iñaki García-Arrizabalaga +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
World ecology and global environmental governance [PDF]
Environmental problems have always been part of our history, of life, and work. Yet the way in which environmental problems are perceived and politicized has changed: If it was at first chiefly local and regional environmental problems that were ...
Brühl, Tanja, Simonis, Udo E.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

