Results 191 to 200 of about 445,227 (253)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Aligning attitudes and actions: experience of extreme weather events raises environmental concerns and pro-environmental behaviors of residents. [PDF]

Front Public Health
Hu S, Duan P, Meng Y, Zhou Z.
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Toward standardized environmental detection of antibiotics and ARGs for regulatory interpretation and concern tiering. [PDF]

Front Microbiol
Pi N, He X, Zhang J, Zhu L, Wu X, Yang L, Li Y, Xiang R, Wu X.   +8 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Concern about the potential environmental impact of a large-scale war among Latin American adults. [PDF]

BMC Public Health
Mejía CR, Serna-Alarcón V, Yáñez JA, Davies NM, Cedillo-Balcázar J, Useche-Villamizar D, Vega-Useche C.   +6 more
europepmc   +1 more source

Nature Relatedness as an Orientation in Moral Psychology. [PDF]

Integr Psychol Behav Sci
Janhonen J, Kähönen J, Salmi I.
europepmc   +1 more source

Social and experiential factors linked to concern about climate-related health harm in the United States. [PDF]

Health Aff Sch
Stimpson JP, Ortega AN.
europepmc   +1 more source

Chemicals of Concern in Chemical Hair Straightening Products: A Scoping Review. [PDF]

Curr Environ Health Rep
Weaver E, Chan M, Edwards L, Zota AR.
europepmc   +1 more source