Results 51 to 60 of about 2,204,410 (311)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

HARMONIZATION OF ENVIRONMENTAL MANAGEMENT ACCOUNTING - TOOL FOR MANAGING ECONOMIC RECONFIGURATION [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2021
The market economy implies the permanent optimization of an accounting system that ensures: modern methods, policies, and strategies compatible with the requirements of the current economy oriented towards the support of longterm sustainable economic ...
ANA-MARIA COMÂNDARU (ANDREI), ADRIANA PADURARU (HORAICU)   +1 more
doaj  

Achieving economic and environmental sustainability through optimum balance of costs [PDF]

, 2011
Awareness and significance of sustainable development (SD) has been growing around the world for the last few decades. Sustainable construction is now considered a way for the construction industry to contribute to this larger effort. It is clear why the
Ekundayo, Damilola, Perera, Srinath, Udeaja, Chika, Zhou, Lei   +3 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Achieving the economic-environmental harmonization in firm through environmental costs [PDF]

Acta Montanistica Slovaca, 2005
The paper presents basic points of the economic-environmental organization aimed at the creation of conditions for the harmonization of economic and environmental plans of the firm.
Katarína Teplická
doaj  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Protection of the natural environment on the expressway S17

Budownictwo i Architektura, 2014
Article describes S17 expressway environmental aspects. The paper presents two, adjacent to each other S17 sections, “Kurów Zachód” - “Jastków” and “Jastków” - “Lublin Sławin”, in the Lublin Province.
Maciej Kowal
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Mathematical model for identifying and quantifying the overall environmental cost

Journal of Business Economics and Management, 2020
The paper deals with the environmental costs (EC) in the electrical equipment industry by using environmental accounting as a strategic instrument for controlling the economic entity (EE).
Sorinel Capusneanu, Dan Ioan Topor, Mihaela Stefan Hint, Constantin Aurelian Ionescu, Mihaela Denisa Coman, Liliana Paschia, Nicoleta Luminita Gudanescu Nicolau, Oana Raluca Ivan   +7 more
doaj   +1 more source