Results 111 to 120 of about 2,273 (218)

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Spatial Modeling of Olive Oil Polyphenol Content and Phenolic Terroirs Using Empirical Bayesian Kriging Regression Prediction

Agronomy
Following the 2021 Montiferru wildfire, one of the largest wildfire events in modern Italian history, assessing the suitability of olive-growing environments for high-quality extra virgin olive oil (EVOO) production is crucial for supporting sustainable ...
Marco Campus, Fabio Piras, Gianluigi Pili, Michele Fiori, Giovanni Bussu, Damiano Muru, Giorgia Damasco, Francesca Frongia, Piergiorgio Sedda, Emanuele Cauli   +9 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Non-Growing Season Surface Soil Salinity Estimation: Integrating Multi-Source Remote Sensing Data and Convolutional Neural Network Models in Arid Agricultural Areas

Agronomy
Soil salinization reduces crop productivity and threatens agricultural sustainability in arid regions. Reliable estimation of farmland soil salinity is therefore essential for salinization monitoring and land management.
Wanzhi Zhou, Xinjun Wang, Wenli Dong, Songrui Ning, Chenyu Li, Yu Huang, Jiandong Sheng   +6 more
doaj   +1 more source

Temperature‐Modulated MEMS Gas Sensor Array Enabled by Physics‐Informed Deep Learning for Thermal‐Runaway Characteristic Gas Discrimination

Advanced Science, EarlyView.
This work presents a 2 × 2 integrated single‐chip MEMS gas sensor array with temperature modulation and deep learning for discriminating thermal‐runaway characteristic gases. The array generates distinct temperature‐modulated response patterns for four characteristic gases (H2, CO, CH4, and CO2), while a HK‐MoE model is developed to achieve robust ...
Qin Luo, Qi Guo, Rongyue Liu, Yilin Li, Haiping Zhu, Wei Zhang, Zhongren Chen, Zhaojun Liu, Xing Cheng   +8 more
wiley   +1 more source

Machine Learning-Based Spatial Mapping of Soil Organic Carbon and Its Climatic and Topographic Drivers in the Arid Regions

Remote Sensing
Digital soil mapping (DSM) is an effective approach for assessing soil organic carbon (SOC) at regional scales. With the increasing availability of geospatial datasets, a growing number of environmental covariates have been incorporated into SOC mapping.
Yuqing Chen, Haiyang Xi, Bin Wang, Wenju Cheng, Yuanyuan Xue, Yulian Hao, Linbo Qu, Meng Zhu   +7 more
doaj   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

The Effects of Seasonality and Environmental Covariates on Two Heterodon Species

Proceedings of the West Virginia Academy of Science
   Seasonal and demographic activity patterns in snakes are heavily influenced by environmental variables. Members of the same genus, such as Heterodon, may differ in activity patterns within the same site. This study focuses on the seasonal patterns kept by a population of H. platirhinos and an endangered population of H. nasicus in southeastern Iowa.
Stanley Bielinski, Zachary Loughman
openaire   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source