Results 111 to 120 of about 163,360 (309)
Social inequalities and the environmental crisis: need for an intergenerational alliance: Tenth anniversary of Frontiers in Public Health. [PDF]
Front Public Health, 2023 Vineis P, Gambhir A.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Comment on "A global environmental crisis 42,000 years ago". [PDF]
Science, 2021 Picin A +9 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
From Stockholm to Kyoto and Beyond : A Review of the Globalisation of Global Warming Policy and North-South Relation [PDF]
, 2008 Previously published as a special issue of Globalizations, this collection of essays addresses what is arguably the most pressing and urgent issue of our day - the continuing development of global environmental crises and the need for new and urgent ...
Linnér, Björn-Ola,, Jacob, Merle,
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Plastic Waste and the Environmental Crisis Industry. [PDF]
Crit Criminol, 2021 Smith O, Brisman A.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Measuring the Environmental Impacts of Changing Trade Patterns on the Poor [PDF]
It is an empirical fact that it is very difficult to balance economic growth, poverty reduction, and environment protection, particularly for developing and transitional economies.
Singh, Kanhaiya +2 more
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