Results 121 to 130 of about 1,261,918 (306)

Synthesis of Diindolylmethanes (DIMs) Catalyzed by Silicotungstic Acid by Grinding Method

E-Journal of Chemistry, 2010
The synthesis of diindolylmethanes (DIMs) via the condensation of indole and aromatic aldehydes catalyzed by silicotungstic acid was carried out in 68%~98% yields at room temperature within 1~5 min by grinding.
Ji-Tai Li, Shao-Feng Sun
doaj   +1 more source

A sustainable management model based on business excellence as applied to mining companies

, 2010
The success of a sustainable business project depends on different factors but there is no doubt that the excellence of business management is the single most critical factor, because of it is what connects all the others.
Botin Gonzalez, Jose Antonio, Herrandiz, Francisco   +1 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Differentiated effects and mechanisms of N-, P-, S-, and Fe-modified biochar materials for remediating Cd- and Pb-contaminated calcareous soil

Ecotoxicology and Environmental Safety
To investigate the remediation effects of various modified biochar materials derived from different impregnation agents on Cd- and Pb-contaminated calcareous soil, nitrogen (N-), phosphorus (P-), sulfur (S-), and iron (Fe-) modified biochar materials ...
Amir Bostani, Xingying Meng, Le Jiao, Srđan D. Rončević, Peng Zhang, Hongwen Sun   +5 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Structural damage diagnosis under changing environmental conditions

, 2004
A method is proposed to perform structural health monitoring under varying environmental and operational conditions. The method is based on principal component analysis (PCA) applied to a data set containing vibration characteristics identified during the monitoring of the structure.
Yan, A. M., Kerschen, Gaëtan, De Boe, Pascal, Golinval, Jean-Claude   +3 more
openaire   +1 more source

Home for Good? Preparing to Support People with Learning Difficulties in Residential Settings when they Develop Dementia [PDF]

, 2004
This report explores the findings of a study which investigated the current models of practice for supporting people with learning difficulties and dementia living in care home settings.
Catherine Rae, Colm Cunningham, Diana Kerr, Heather Wilkinson   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source