Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Conflicts of Interest, Funding Support, and Author Affiliation in Peer-Reviewed Research on the Relationship between Climate Change and Geophysical Characteristics of Hurricanes. [PDF]
Weinkle J +5 more
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
A full belly counsels well: More stabilisation with more responsibility. [PDF]
Sheng X.
europepmc +1 more source
Female leadership and ESG rating disagreement: Evidence from China. [PDF]
Liao W, Chen S.
europepmc +1 more source
The Impact of Green FinTech Promote Corporate Carbon Neutrality: Evidence from the Perspective of Financing Incentives and Scale Quality. [PDF]
Zhuang L, Wu C.
europepmc +1 more source
Interpretable predictive model for listed companies ESG greenwashing based on XGBoost and SHAP. [PDF]
Jianfeng Z, Tiantian Q.
europepmc +1 more source
Navigating identity and professional life: A qualitative study of LGBTQ+ genetic counselors' workplace experiences. [PDF]
Nelson KL, Zayhowski K, MacFarlane IM.
europepmc +1 more source
Not just a covariate: circadian photoreception varies by age and sex. [PDF]
Wescott D.
europepmc +1 more source

