Results 71 to 80 of about 5,124,119 (207)

Do Board's Corporate Social Responsibility Strategy and Orientation Influence Environmental Sustainability Disclosure? UK Evidence [PDF]

, 2017
The environmental implications of corporate economic activities have led to growing demands for firms and their boards to adopt sustainable strategies and to disseminate more useful information about their activities and impacts on environment.
Akrum Helfaya, Helfaya, A., Helfaya, Ekara, Moussa, Tantawy, Tantawy Moussa, Moussa, T.   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Role of Environmental Disclosure in Mediating Independent Commissioners and Environmental Costs on Profitability

AFRE (Accounting and Financial Review)
This study aims to determine the effect of the independent board of commissioners and environmental costs on profitability through environmental disclosure either directly or indirectly in construction industry companies listed on the Indonesia Stock ...
dhela septian anggaretta, Siti Anisyah, Amin Pujiati, Sucihatiningsih Dian Wisika Prajanti   +3 more
doaj   +1 more source

Sustainability disclosure and reputation: a comparative study [PDF]

This paper aims to explore the relationship between a company’s sustainability disclosure and its reputation. The sample consists of 57 companies in the Dow Jones Sustainability Index (DJSI) and a control group belonging to the Dow Jones Global Index ...
Giovanna Michelon
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Effects of environmental information disclosure on pollution reduction and carbon emission reduction [PDF]

Ziyuan Kexue
[Objective] The synergistic enhancement of pollution reduction and carbon emission mitigation serves as the general approach to promote the comprehensive green transformation of economic and social development. The importance of environmental information
SHAO Hanhua, WANG Yaning
doaj   +1 more source

Does Disclosure Reduce Pollution? Evidence from India's Green Rating Project [PDF]

Public disclosure programs that collect and disseminate information about firms’ environmental performance are increasingly popular in both developed and developing countries.
Blackman, Allen, Narain, Urvashi, Lyon, Thomas P., Powers, Nicholas   +3 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source