Results 71 to 80 of about 459,614 (310)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

KUALITAS PENGUNGKAPAN LINGKUNGAN : PERSPEKTIF DARI KINERJA LINGKUNGAN, CORPORATE GOVERNANCE , DAN RELEVANSI NILAI [PDF]

open access: yes, 2016
This research aims to investigate the influence of environmental disclosure as dependence and independence variables. First investigation, it examines the influence of environmental performance and corporate governance on environmental disclosure ...
PRAMESTI, Ajeng Hilarysa   +1 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Effects of environmental information disclosure on pollution reduction and carbon emission reduction [PDF]

open access: yesZiyuan Kexue
[Objective] The synergistic enhancement of pollution reduction and carbon emission mitigation serves as the general approach to promote the comprehensive green transformation of economic and social development. The importance of environmental information
SHAO Hanhua, WANG Yaning
doaj   +1 more source

PENGARUH ENVIRONMENTAL PERFORMANCE DAN ECONOMIC PERFORMANCE TERHADAP ENVIRONMENTAL DISCLOSURE (Studi Empiris pada Perusahaan Manufaktur yang terdaftar di Bursa Efek Indonesia Periode 2010-2012) [PDF]

open access: yes, 2013
This study aims to obtain empirical evidence about the effect of environmental performance and economic performance to environmental dislosure.
AL FIKHRI, DITIS
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

FAKTOR-FAKTOR YANG MEMPENGARUHI KEBIJAKAN PENGUNGKAPAN TANGGUNG JAWAB SOSIAL DAN LINGKUNGAN PADA PERUSAHAAN MANUFAKTUR DI BURSA EFEK INDONESIA

open access: yesJurnal Ilmiah Akuntansi dan Bisnis, 2012
Social and environmental responsibility has become one of disclosure component required for listing on Indonesia Stock Exchange (BEI). Disclosure is done on annual or sustainability report.
AGUNG SUARYANA
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analisis Pengaruh Ukuran Perusahaan, Leverage, Profitabilitas, dan Tipe Industri Terhadap Environmental Disclosure (Studi Empiris Pada Perusahaan yang Terdaftar di PROPER dan BEI Tahun 2011 – 2013) [PDF]

open access: yes, 2015
This study analyze the Effect Analysis Company Size, Profitability, Leverage, and Industry Type Against Environmental Disclosure. The purpose of this study was to analyze the Environmental Disclosure in Indonesia premises review the annual report of each
KISWARA, Endang, PAMBUDI, Waskito Bagus
core  

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