Results 71 to 80 of about 464,272 (311)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Pengaruh Environmental Performance terhadap Environmental Disclosure dan Hard Environmental Disclosure Perusahaan [PDF]
, 2013 The objective of this study is to determine the impact of environmental performance to the level of environmental disclosures and the level of hard environmental disclosures. Disclosure is scored using an index developed by Clarkson et al. (2008) and the
Gladia, P. (Prima), Rahardja, S. (Surya)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Environmental performance rating and disclosure - China's green-watch program [PDF]
This paper describes a new incentive-based pollution control program in China in which the environmental performance of firms is rated and reported to the public.
Dong Cao +6 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Jurnal Ilmiah Akuntansi dan Bisnis, 2012 Social and environmental responsibility has become one of disclosure component required for listing on Indonesia Stock Exchange (BEI). Disclosure is done on annual or sustainability report.
AGUNG SUARYANA
doaj
Effects of environmental information disclosure on pollution reduction and carbon emission reduction [PDF]
Ziyuan Kexue[Objective] The synergistic enhancement of pollution reduction and carbon emission mitigation serves as the general approach to promote the comprehensive green transformation of economic and social development. The importance of environmental information
SHAO Hanhua, WANG Yaning
doaj +1 more source
Pengaruh Pengungkapan Sosial dan Lingkungan terhadap Asimetri Informasi Bagi Investor (Studi Empiris pada Perusahaan Manufaktur yang Terdaftar di Bei Tahun 2012-2013) [PDF]
, 2015 This research aimed to examine the effect of disclosure of social and environmental disclosure to the asymmetry of information in the annual report issued by the company.
Almira, L. F. (Lida), Fuad, F. (Fuad)
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source