Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
A novel Complex q-rung orthopair fuzzy Yager aggregation operators and their applications in environmental engineering. [PDF]
HeliyonAhmmad J +3 more
europepmc +1 more source
Accurate and reliable estimation of kinetic parameters for environmental engineering applications: A global, multi objective, Bayesian optimization approach. [PDF]
MethodsX, 2019 Manheim DC, Detwiler RL.
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Handbook of environmental engineering assessment : strategy, planning, and management /
, 2012 This is one of the most comprehensive books on complex subjects of environmental engineering assessment and planning. Addressing these issues requires an understanding of technical, economic, and policy perspectives; based upon extensive research and ...
Jain, Ravi
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Using environmental engineering to increase hand hygiene compliance: a cross-over study protocol. [PDF]
BMJ Open, 2017 Schmidtke KA +8 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Mitigating Climate Change at the Carbon Water Nexus: A Call to Action for the Environmental Engineering Community. [PDF]
Environ Eng Sci, 2016 Clarens AF, Peters CA.
europepmc +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
, 2000 In recent years, artificial neural networks (ANNs) have been applied to many geotechnical engineering problems and have demonstrated some degree of success.
Shahin, Mohamed Amin +2 more
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