Results 251 to 260 of about 4,559,142 (274)

A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment. [PDF]

Nat Commun
Pérez RF, Tezanos P, Peñarroya A, González-Ramón A, Urdinguio RG, Gancedo-Verdejo J, Tejedor JR, Santamarina-Ojeda P, Alba-Linares JJ, Sainz-Ledo L, Roberti A, López V, Mangas C, Moro M, Cintado Reyes E, Muela Martínez P, Rodríguez-Santamaría M, Ortea I, Iglesias-Rey R, Castilla-Silgado J, Tomás-Zapico C, Iglesias-Gutiérrez E, Fernández-García B, Sanchez-Mut JV, Trejo JL, Fernández AF, Fraga MF.   +26 more
europepmc   +1 more source

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

Advanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie, Jingyi Ju, Zhenxing Wang, Jun Chen, Lin‐Ping Wu, Jiaming Sun   +5 more
wiley   +1 more source

Can Environmental Enrichment Modulate Epigenetic Processes in the Central Nervous System Under Adverse Environmental Conditions? A Systematic Review. [PDF]

Cell Mol Neurobiol
de Sousa Fernandes MS, Costa MR, Badicu G, Yagin FH, Santos GCJ, da Costa JM, de Souza RF, Lagranha CJ, Ardigò LP, Souto FO.   +9 more
europepmc   +1 more source

Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche

Advanced Healthcare Materials, EarlyView.
Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson, Victoria R. Barnhouse, Sydney K. Bierman, Brendan A.C. Harley   +3 more
wiley   +1 more source

Investigating the impact of environmental enrichment on proteome and neurotransmitter-related profiles in an animal model of Alzheimer's disease. [PDF]

Aging Cell
Nam Y, Kim S, Park YH, Kim BH, Shin SJ, Leem SH, Park HH, Jung G, Lee J, Kim HG, Yoo DH, Kim HS, Moon M.   +12 more
europepmc   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Global Overview of Environmental Enrichment Studies: What Has Been Done and Future Directions. [PDF]

Animals (Basel)
Bachetti ÉDS, Viol LY, Viana-Junior AB, Young RJ, de Azevedo CS.   +4 more
europepmc   +1 more source

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

Advanced Materials, EarlyView.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew, Erlantz Lizundia, Mark J. MacLachlan   +2 more
wiley   +1 more source

Implications of Lairage and Environmental Enrichment on Behavioral Responses and Skin Lesions in Finishing Pigs in a Slaughterhouse. [PDF]

Animals (Basel)
Sobral VS, Silveira RMF, Guesine GD, Arno A, de Azevedo KAM, Lobos CMV, da Silva IJO.   +6 more
europepmc   +1 more source

Polyphenol‐Derived Carbonaceous Frameworks with Multiscale Porosity for High‐Power Electrochemical Applications

Advanced Materials, EarlyView.
This review examines the fluid dynamic behavior within carbonaceous porous structures, linking structural characteristics to electrolyte transport and electrochemical performance. Specifically, it quantitatively assesses the effect of polyphenol derivatives‐harnessed multiscale pore structures on active surface utilization and electrochemical activity ...
Minjun Kim, Joon Ho Jang, Myeong Gyun Nam, Pil J. Yoo   +3 more
wiley   +1 more source