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Developmental Exposure to Environmental Toxicants
Pediatric Clinics of North America, 2015Children interact with the physical environment differently than adults, and are uniquely susceptible to environmental toxicants. Routes of absorption, distribution, metabolism, and target organ toxicities vary as children grow and develop. This article summarizes the sources of exposure and known adverse effects of toxicants that are ubiquitous in our
Alison J, Falck +5 more
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Environmental lead exposure and the kidney
Journal of Toxicology: Clinical Toxicology, 1988Lead and its components remain widely distributed in the environment and in some workplaces. Lead serves no useful physiological function, yet is potentially toxic to several organ systems. For many years human health effects have been recognized after heavy lead exposure.
B P, Bernard, C E, Becker
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Childhood Exposure to Environmental Lead
19741 to 5% of urban adults have blood lead values ≥ 40 μgPb/100 ml whole blood whereas approximately 25% of urban children have blood leads at this level. The metabolic exposure (μgPb/kg body weight) of children is over three times adult exposure for assumed normal absorption and ingestion of lead and twice the exposure of adults for inhaled lead.
D K, Darrow, H A, Schroeder
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Mitochondrial Epigenetics and Environmental Exposure
Current Environmental Health Reports, 2016The rising toll of chronic and debilitating diseases brought about by the exposure to an ever expanding number of environmental pollutants and socio-economic factors is calling for action. The understanding of the molecular mechanisms behind the effects of environmental exposures can lead to the development of biomarkers that can support the public ...
Lambertini L, Byun HM
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The Epidemiology of Pediatric Environmental Exposures
Pediatric Clinics of North America, 2007Currently, the only national databases that are available to aid in a search to assess the effect of environmental exposures on children's health are those provided by the Pediatric Environmental Health Specialty Units and poison control centers. Both have limitations and are largely deficient in accurate, helpful numbers.
Kathryn, Veal +2 more
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Environmental exposures and prostate cancer
Urologic Oncology: Seminars and Original Investigations, 2012Many malignancies have been linked to specific environmental exposures. Several environmental and occupational factors have been studied for an association to prostate cancer (CaP) risk. These include Agent Orange exposure, farming and pesticides, sunlight/ultraviolet radiation, as well as trace minerals used in tire and battery manufacturing.
Jeffrey K, Mullins, Stacy, Loeb
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Biomarkers of Environmental Exposures in Blood
2019Exposure to environmental pollution is recognized as a significant contributor to the burden of disease in the general population. Biomonitoring of chemical concentrations in human tissues and matrices is a powerful tool for measuring exposure to chemicals in a population.
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