Results 161 to 170 of about 71,585 (251)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Challenges in assessing the effects of environmental governance systems on conservation outcomes. [PDF]

Conserv Biol
Ayambire RA, Rytwinski T, Taylor JJ, Luizza MW, Muir MJ, Cadet C, Armitage D, Bennett NJ, Brooks J, Cheng SH, Martinez J, Nagendran M, Öckerman S, Rivera SN, Savage A, Wilkie DS, Cooke SJ, Bennett JR.   +17 more
europepmc   +1 more source

Corporate environmental governance scheme and investment efficiency over the course of COVID-19. [PDF]

Financ Res Lett, 2022
Liu H, Jiang J, Xue R, Meng X, Hu S.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Government environmental governance, fiscal decentralization, and carbon intensity of the construction industry. [PDF]

Sci Rep
Sun Y, Liu M, Lv Y.
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Intellectual capital, digital transformation and firms' financial performance: Evidence from ecological protection and environmental governance industry in China. [PDF]

PLoS One
Yin J, Xu J.
europepmc   +1 more source

The Guarantee Mechanism of China's Environmental Protection Strategy from the Perspective of Global Environmental Governance-Focusing on the Punishment of Environmental Pollution Crime in China. [PDF]

Int J Environ Res Public Health, 2022
An R, Sang T.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source