Results 41 to 50 of about 131,659 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Public Health ChallengesTobacco farming and tobacco control are closely inter‐related issues, particularly in developing countries that are heavily reliant on tobacco farming like Malawi.
Chimwemwe Ngoma +3 more
doaj +1 more source
Green Victimology Perspective the Law Number 32 of 2009 on Environmental Protection and Management
Jurnal Media Hukum, 2020 Green victimology refers to the study of victimology that focuses on victims of environmental harm. The object of this new study cannot be separated from the philosophical values that underlie the growth of green victimology. Through literature research
Angkasa Angkasa
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hearing the Voices of Environmental Harm from Oceania: The Potential of Restorative Justice
International Journal for Crime, Justice and Social DemocracyThis article explores the potential of restorative justice as a vehicle through which to hear stories of environmental harm from Oceania. Conferencing, a restorative justice process, is a face-to-face dialectic exchange where people are heard, their ...
Mark Hamilton
doaj +1 more source
Beyond Litigation: The Need for Creativity in Working to Realise Environmental Rights [PDF]
Law, Environment and Development Journal, 2017 Environmental harm is one of the biggest challenges facing communities living in poverty across the world. Unfortunately, in developing strategies to combat environmental harm, the lawyers that support such communities often tend to focus purely on ...
Lisa Chamberlain
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
International Review of the Red CrossThe legal appraisal of civilian mental harm amounting to trauma is something that has been discussed by international scholars when it comes to warfare and its aftermath, but no discussion has taken place on how such civilian war trauma can be ...
Solon Solomon
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source