Results 261 to 270 of about 4,497,175 (353)
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee+3 more
wiley +1 more source
The Impact of Rolling Blackouts on Environmental Health in South Africa. [PDF]
Wright CY+9 more
europepmc +1 more source
The necessity for environmental health planning.
Emil T. Chanlett+2 more
openalex +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez+5 more
wiley +1 more source
Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era. [PDF]
Yu M, Fang M, Wang B.
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Breathing life into learning about air quality: developing and implementing environmental health outreach with high school students. [PDF]
Hoskins K, Dang N, Molla F.
europepmc +1 more source
Health and Safety Laboratory environmental quarterly, June 1, 1975-- September 1, 1975
E.P. Hardy
openalex +2 more sources
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul+3 more
wiley +1 more source