Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A report on the evaluation of the environmental impact based on life cycle assessments (LCA) according to ISO 14040 /44.
Prutha Prashant Kulkarni +1 more
openaire +3 more sources
INSECT POPULATION DYNAMICS, PESTICIDE USE AND FARMWORKER HEALTH REVISITED: PESTICIDE CHOICE AND RISK MITIGATION [PDF]
Several policies to reduce worker exposure, dietary and environmental risks are examined in the context of pesticide choice driven by insect population dynamics.
Wyatt, T.J.
core +1 more source
Environmental Justice in Indian Country: Using Equity Assessments to Evaluate Impacts to Trust Resources, Watersheds and Eco-cultural Landscapes [PDF]
, 1999 Native American cultures, genetics, nutrition, and ways of life co-evolved with their natural systems through thousands of years. This process has resulted in seamless eco-cultural systems of humans, plants, animals, rivers, landforms, and air sheds ...
Barbara Harper, Stuart Harris
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
”How much is enough?” Determining Adequate Levels of Environmental Compensation for Wind Power Impacts using Equivalency Analysis: An Illustrative & Hypothetical Case Study of Sea Eagle Impacts at the Smøla Wind Farm, Norway [PDF]
Environmental considerations at wind power require avoidance and mitigation of environmental impacts through proper citing, operational constraints, etc. However, some impacts are unavoidable for otherwise socially-beneficial projects.
Cole, Scott
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
On the drivers of ice nucleating particle diurnal variability in Eastern Mediterranean clouds
npj Climate and Atmospheric ScienceWe report the drivers of spatiotemporal variability of ice nucleating particles (INPs) for mixed-phase orographic clouds (~−25 °C) in the Eastern Mediterranean.
Kunfeng Gao +11 more
doaj +1 more source
A Review of Hydroponics and Conventional Agriculture Based on Energy and Water Consumption, Environmental Impact, and Land Use [PDF]
, 2023 Dimitra I. Pomoni +3 more
openalex +1 more source
A Sustainability Framework for Enhancing the Long-Term Success of LULUCF Projects [PDF]
Collateral impacts of LULUCF projects, especially those concerning social and environmental aspects, have been recognised as important by the Marrakech Accords. The same applies to the necessity of assessing and, if possible, of quantifying the magnitude
Bart Muys +4 more
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