Results 271 to 280 of about 13,671,980 (384)

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Optimizing diets for finishing pigs: balancing ideal protein to enhance growth performance and reduce environmental impacts. [PDF]

Transl Anim Sci
Mulvenna CC, McCormack UM, McCracken KJ, Smyth S, Gordon FJ, Beattie VE, Bradford R, Sungirai M, Magowan E, Muns R, Ball E.   +10 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Assessing the Nutritional and Environmental Impacts of Major UK Food and Beverage Manufacturers

Hammond E, Bandy LK, Milner-Gulland E, Pechey R, Rayner M, Scarborough P, Jain S, Clark M.   +7 more
europepmc   +1 more source

Alpine Grassland Growth and Its Ecological Responses to Environmental Impacts: Insights from a Comprehensive Growth Index and SHAP-Based Analysis. [PDF]

Plants (Basel)
Li Y, Liu Y, Li X, Yan J, Du Y, Meng Y, Liu J.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Geometric stoichiometry model yields relevant insights for assessing nutrient-related environmental impacts of aquaculture. [PDF]

Conserv Physiol
Prasad SS, Cameron DD, Carter CG, Williamson A, Blanchard JL.   +4 more
europepmc   +1 more source

Summary of the Nuclear Risk Assessment for the Mars 2020 Mission Environmental Impact Statement.

, 2015
Daniel James Clayton, John Bignell, Christopher Jones, Daniel Rohe, Gregg Flores, Timothy Bartel, Fred Gelbard, San Le, Charles Morrow, Donald L. Potter, Larry W. Young, Nathan E. Bixler, Ronald J. Lipinski   +12 more
openalex   +1 more source

The Impact of Green Product Innovation on Firm Performance and Competitive Capability: The Moderating Role of Managerial Environmental Concern

, 2012
İlker Murat Ar
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source