Results 61 to 70 of about 6,610,875 (302)

Environmental Impacts—Terrestrial Ecosystems [PDF]

, 2016
The chapter starts with a discussion of general patterns and processes in terrestrial ecosystems, including the impacts of climate change in relation to productivity, phenology, trophic matches and mismatches, range shifts and biodiversity. Climate impacts on specific ecosystem types—forests, grasslands, heathlands, and mires and peatlands—are then ...
Hölzel, N., Hickler, T., Kutzbach, L., Joosten, H., van Huissteden, J., Hiederer, R.   +5 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Environmental Impacts—Lake Ecosystems [PDF]

, 2016
The North Sea region contains a vast number of lakes; from shallow, highly eutrophic water bodies in agricultural areas to deep, oligotrophic systems in pristine high-latitude or high-altitude areas. These freshwaters and the biota they contain are highly vulnerable to climate change.
Adrian, Rita, Hessen, Dag Olav, Blenckner, Thorsten, Hillebrand, Helmut, Hilt, Sabine, Jeppesen, Erik, Livingstone, David M., Trolle, Dennis   +7 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Assessing the Environmental Impacts of Palm Oil

, 2011
Palm oil is used for cooking in Southeast Asia and Africa and as a food additive in a number of processed foods world-wide. The production of palm oil is increasing, and it is of special interest from a nutritional point of view due to its high energy ...
Fröling, Morgan,, Fransson, Kristin,, Svanström, Magdalena,, Arvidsson, Rickard,   +3 more
core   +7 more sources

A scalable method for identifying key indicators to assess urban environmental sustainability: A case study in Norway

City and Environment Interactions
Urbanization presents numerous societal challenges and exacerbates environmental issues. It is crucial to comprehend the current state and future direction of cities to formulate strategies and actions that mitigate negative consequences while ensuring a
Hai-Ying Liu, Babak Ebrahimi
doaj   +1 more source

The Effect of Shading and Nutrient Addition on the Microphytobenthos, Macrofauna, and Biogeochemical Properties of Intertidal Flat Sediments

Frontiers in Marine Science, 2020
Proliferation of urban structures and mangrove forests in estuaries are altering the shading of intertidal sediments. Urbanization also tends to increase nutrient loads in estuaries, which can have numerous direct and indirect effects on estuarine flora ...
Trevor J. Tolhurst, Trevor J. Tolhurst, M. G. Chapman, R. J. Murphy   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source