Results 181 to 190 of about 6,227,014 (305)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

National report on biochemical indicators of diet and nutrition in the U.S. population [PDF]

The National Report on Biochemical Indicators of Diet and Nutrition in the U.S. Population is a series of publications that provide ongoing assessment of the U.S.
National Center for Environmental Health (U.S.) Division of Laboratory Sciences.
core  

The effect of air pollution and household environmental indicators on anemia status among under-five children in low-middle income countries: exploring potential machine learning applications on demographic and health surveys. [PDF]

Sci Rep
Fenta HM, Kofi Amegah A, Rantala AK, Paciência I, Jaakkola JJK.   +4 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Exploring the influence of environmental indicators and forecasting influenza incidence using ARIMAX models. [PDF]

Front Public Health
Zheng X, Chen Q, Sun M, Zhou Q, Shi H, Zhang X, Xu Y.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Towards Sustainable Mobility Indicators: Application to the Lyons Conurbation [PDF]

This paper applies the theme of sustainable development to the case of urban transport and daily mobility of the inhabitants of a city. A set of indicators which simultaneously takes the three dimensions of sustainability––environmental, economic, and ...
Pascal Pochet, Hélène Poimboeuf, Jean-Pierre Nicolas   +2 more
core  

Epidemiological landscapes in the Amazon: exploring the association between land use, environmental indicators, and vector-borne diseases. [PDF]

Cad Saude Publica
Vitor ACR, Codeço CT, Escada MIS.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A hybrid method of system dynamics and design of experiments for investigating the economic and environmental indicators of electricity industry. [PDF]

Heliyon
Doroodi M, Ostadi B, Husseinzadeh Kashan A, Zegordi SH.   +3 more
europepmc   +1 more source