Results 111 to 120 of about 396,499 (303)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Research trends in environmental information disclosure: A bibliometric analysis

CTU Journal of Innovation and Sustainable Development
This study aimed to investigate the development of environmental information disclosure (EID) research publications from 1992 to 2024 to identify trends and provide valuable insights to researchers in related fields.
Thuy An Nguyen, Senthil Kumar, Shahryar Sorooshian   +2 more
doaj   +3 more sources

Corporate environmental information disclosure and tax avoidance: Evidence from China. [PDF]

Heliyon, 2023
Gu Y, Wang S.
europepmc   +1 more source

THE LANGUAGE OF CORPORATE ENVIRONMENTAL DISCLOSURE: A RESEARCH NOTE [PDF]

We investigate different language techniques used in corporate environmental disclosures and test whether the impression management (see Neu et al., 1998) hypothesis holds when disclosures are measured as such.
Charles H. Cho, Robin W. Roberts
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental information disclosure and corporate performance: Evidence from Chinese listed companies. [PDF]

Heliyon, 2023
Ye Y, Yang X, Shi L.
europepmc   +1 more source

PENGARUH KARAKTERISTIK PERUSAHAAN TERHADAP PENGUNGKAPAN LINGKUNGAN (Studi Empiris Pada Perusahaan Sektor Pertambangan dan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia Tahun 2013-2014) [PDF]

, 2016
This study aims to examine the disclosure of information relating to the environment made by the company are influenced by factors including the size of the company, profitability, liquidity, leverage, the level of tax paid, the size of the public ...
EDDWINA, Muhammad Yudith, LAKSITO, Herry
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The application of RAGA-PP model in environmental accounting information disclosure of enterprises in heavy pollution industries

Results in Engineering
The global concern for environmental protection has driven the demand for corporate environmental accounting information, especially in heavily polluting industries.
Fang Yu, Lina Pei
doaj   +1 more source