Results 151 to 160 of about 857,208 (327)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

News Media as a Channel of Environmental Information Disclosure: Evidence from an EGARCH Approach [PDF]

open access: yes
This paper incorporates EGARCH modeling in a financial event study relating firm value to negative environmental news. News media provide informal information channels unlike formal government disclosure programs.
David I. Stern   +2 more
core  

Difference in Social and Environmental Disclosure between Profit and Non-profit Organisations [PDF]

open access: yes, 2017
There has been a growing concern in the past few decades around the impact of industrial activities on the environment and the society. This situation led corporate management to develop environmental management systems and to incorporate social and ...
France, Adrian, Varghese, Amala
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

ELECTRICITY DEREGULATION: WHAT'S IN STORE FOR THE ENVIRONMENT? [PDF]

open access: yes
We test the: degree to which electricity consumers will trade off price and environmental attributes, effectiveness of environmental certification, and effectiveness of voluntary versus mandatory environmental disclosure.
Austin, Tom   +5 more
core   +1 more source

Sustainability disclosure among Malaysian Shari’ah-compliant listed companies: Web reporting [PDF]

open access: yes, 2009
This paper advances previous research of sustainability disclosure by focusing on information disclosed in the companies’ web site rather than through annual reports. Despite looking at the listed companies in general, this study attempts to consider the
Alwi, Kasumalinda   +2 more
core  

Environmental issues and financial reporting trends: A survey in the chemical and oil & gas industries

open access: yes, 2001
As environmental performance is increasingly seen to have an influence over financial performance and financial risk assessment, disclosure of environmental issues in the Annual Reports is a fundamental requirement for a company in order to satisfy the ...
Galluccio, Giulia, Salomone, Roberta
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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