Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Environmental information disclosure and green transformation: Evidence from Chinese manufacturing enterprises. [PDF]
HeliyonXu H, Fu Y, Li Y, Zhang G, Bi S.
europepmc +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The Impact of Environmental Information Disclosure on the Firm Value of Listed Manufacturing Firms: Evidence from China. [PDF]
Int J Environ Res Public Health, 2020 Yang Y, Wen J, Li Y.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Impact of mandatory environmental information disclosure on the capital cost: Evidence from listed companies in China. [PDF]
HeliyonTian L, Shen Y, Du M.
europepmc +1 more source
Strategic Disclosure of Valuable Information within Competitive Environments [PDF]
Can valuable information be disclosed intentionally by the informed agent even within a competitive environment? In this article, we bring our interest into the asymmetry in reward and penalty in the payoff structure and explore its effects on the ...
Young-Ro Yoon
core
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Peer effect of environmental information disclosure behavior in China:Empirical test based on "Real green" and "Fake green". [PDF]
HeliyonGu C, Shen M.
europepmc +1 more source
, 2010 [[abstract]]Based on agency theory and stewardship theory, this research explores the relationship between corporate governance and corporate social performance.
Guan- Hong Chen
core