Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
The effect of voluntary environmental disclosure on firm value : a study of Nordic listed firms [PDF]
This paper empirically investigates the relationship between voluntary environmental disclosure and firm value. The analysis is based on a sample consisting of Nordic listed firms disclosing environmental information to the Carbon Disclosure Project in ...
Haukvik, Guro Dingsør +1 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Sustainability disclosure and reputation: a comparative study [PDF]
This paper aims to explore the relationship between a company’s sustainability disclosure and its reputation. The sample consists of 57 companies in the Dow Jones Sustainability Index (DJSI) and a control group belonging to the Dow Jones Global Index ...
Giovanna Michelon
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Benefits and Costs of Environmental Information Disclosure: What Do We Know About Right to Know? [PDF]
Following the attacks of September 11, 2001, the Environmental Protection Agency and other government agencies removed information from their websites that they feared could invite attacks on critical public and private infrastructure.
Beierle, Thomas
core
THE INFLUENCE OF PROFITABILITY, LEVERAGE, AND ENVIRONMENTAL PERFORMANCE ON CARBON EMISSION DISCLOSURE (AN EMPIRICAL STUDY ON MANUFACTURING COMPANIES LISTED ON IDX YEAR 2011-2014) [PDF]
This study aimed to obtain empirical evidence regarding the influence of profitability, leverage and environmental performance to the extent of the carbon emission disclosure.
DIAN LISMANA PUTRI
core
Social and environmental disclosure rating in the Libyan oil and gas sector [PDF]
Over the last two decades, as companies have become more responsive to investors' concerns about the environment and corporate social responsibility (CSR), they have started to provide information about the environmental and social impacts of their ...
Abdo, H, Aldrugi, A
core +2 more sources
Information Acquisition and Disclosure of Environmental Risk [PDF]
Abstract Firms often invest resources in acquiring scientific evidence to evaluate the actual (more accurate) risk (i.e., the probability of occurrence) of any potential environmental hazards that might result from their own production processes and use this information in taking optimal preventive measures.
openaire +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

