Results 121 to 130 of about 140,731 (262)

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

open access: yesAdvanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi   +2 more
wiley   +1 more source

Ultrafast Micrometric Laser Structuring of Polymer Surfaces for Highly Organized Skeletal Muscle Tissue Modeling

open access: yesAdvanced Science, EarlyView.
Standard cell culture supports were functionalized by laser‐structuring to generate advanced topographies tailored to skeletal muscle tissue. The physicochemical modifications of the polymeric surfaces and their interactions with cells were thoroughly investigated, confirming both safety and effectiveness in guiding muscle cell organization.
Lucas Duvert   +10 more
wiley   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

open access: yesAdvanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir   +3 more
wiley   +1 more source

Electron‐Rich Nickel Enabled by Charge Transfer in Multimetal Nanostructures for Efficient Ammonia‐to‐Hydrogen Conversion

open access: yesAdvanced Science, EarlyView.
A charge‐transfer‐engineered Ni catalyst derived from an atomically mixed layered precursor enables efficient ammonia‐to‐hydrogen conversion. Cr‐to‐Ni electron transfer creates electron‐rich Ni active sites that favor NH3 adsorption, modify the dehydrogenation energetics, and weaken N2 binding to facilitate product desorption. This electronically tuned
Donghyeok Kim   +9 more
wiley   +1 more source

THE ROLE OF ENVIRONMENTAL INVESTMENT IN NATURAL ENVIRONMENTAL ACTIVITIES

open access: yesBlack Sea Economic Studies, 2020
Valerii Nemchenko, Ihor Rumiantsev
openaire   +1 more source

Hydrogen Production from Ammonia Electrochemical Cracking

open access: yesAdvanced Science, EarlyView.
NH3 electrochemical cracking (e‐cracking) is a complementary technique to centralized thermal cracking for releasing H2 from NH3. In this article, we review recent advances in catalyst development for these cracking techniques and conduct a techno‐economic analysis (TEA) to evaluate the economic feasibility of e‐cracking.
Yike Ye   +4 more
wiley   +1 more source

Enzyme‐Linked Cycloaddition Assay (ELCA) for Rapid, Ultra‐Sensitive Monitoring of Secreted Sialoglycoproteins

open access: yesAdvanced Science, EarlyView.
Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Jon Lundstrøm   +2 more
wiley   +1 more source

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