Results 91 to 100 of about 850,975 (342)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

“Just” ecopreneurs: re-conceptualising green transitions and entrepreneurship [PDF]

open access: yes, 2016
© 2016 Informa UK Limited, trading as Taylor & Francis Group. Economic, environmental, and social limits of the current capitalist mode of production have led to a rethinking and reconceptualisation of economic processes and models including the role ...
Affolderbach, Julia, Krueger, Rob
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Between activism and science: grassroots concepts for sustainability coined by Environmental Justice Organizations

open access: yesJournal of Political Ecology, 2014
In their own battles and strategy meetings since the early 1980s, EJOs (environmental justice organizations) and their networks have introduced several concepts to political ecology that have also been taken up by academics and policy makers.
Joan Martinez-Alier   +17 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

A framework for advancing the science of environmental justice along the international wildlife trade pathway

open access: yesFrontiers in Conservation Science
The international wildlife trade can be a significant driver of biodiversity loss, as well as a facilitator of zoonotic disease transmission with pandemic potential. Environmental justice has never been more relevant to the wildlife trade as it is today.
Inés Arroyo-Quiroz   +3 more
doaj   +1 more source

2011 State of Metropolitan Housing Report [PDF]

open access: yes, 2011
Examines issues of environmental justice and 2011 indicators of housing affordability in the Louisville area, including concentration of subsidized housing, segregation, poverty, homeownership, foreclosure, and homelessness.

core  

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