Results 51 to 60 of about 850,975 (342)

Racionalidad y Justicia Ambiental: La Elusiva Injusticia de la Vida

Historia Ambiental Latinoamericana y Caribeña, 2021
Law is not justice, says the Manifesto for Life. The justice system established in modernity (the legality of a positive law) does not manage to contain the will to dominate exercised by the ontological regime of modernity over the degradation of life ...
Enrique Leff
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Evolution of the environmental justice movement: activism, formalization and differentiation

Environmental Research Letters, 2015
To complement a recent flush of research on transnational environmental justice movements, we sought a deeper organizational history of what we understand as the contemporary environmental justice movement in the United States. We thus conducted in-depth
Alejandro Colsa Perez, Bernadette Grafton, Paul Mohai, Rebecca Hardin, Katy Hintzen, Sara Orvis   +5 more
doaj   +1 more source

Epilogue [PDF]

, 2009
The Environmental Responsibility Reader is a definitive collection of classic and contemporary environmental works that offers a comprehensive overview of the issues involved in environmental responsibility, steering the reader through each development ...
Blackmore, Chris, Reynolds, Martin, Smith, Mark   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

HARMONIZATION OF METHODOLOGICAL APPROACHES TO THE PROVISION OF FORENSIC SCIENCE SERVICES IN VIEW OF THE RECENTLY ADOPTED NEW EDITION OF THE CIS MEMBER STATES MODEL LAW “ON ENVIRONMENTAL INSURANCE”

Теория и практика судебной экспертизы, 2015
The paper looks at various approaches to developing environmental forensics in implementation of the Model Law «On Environmental Insurance» on trans-boundary territories.
I. Yazhlev, N. Kutuzova, N. Mikhaleva, G. Omelyanyuk   +3 more
doaj  

A Conceptual Approach to Education for Social and Environmental Justice

Revista Internacional de Educación para la Justicia Social, 2018
Social Justice and Environmental Justice are two strongly intertwined approaches that can be considered only one. In this paper, we address the conceptualization of the term of Social and Environmental Justice, as a whole, based on the review of four ...
Sergio Carneros, F. Javier Murillo, Irene Moreno-Medina   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source