Results 51 to 60 of about 126,396 (286)

Evaluation of solid waste generation and management in municipalities of the Lake District in the state of Rio de Janeiro

Boletim do Observatório Ambiental Alberto Ribeiro Lamego, 2013
The Lake District (“Região dos Lagos”) in the State of Rio de Janeiro does not have a waste inventory or any systemized reliable data related to waste generation.
Luiz Carlos Teixeira Júnior, Paulo Rogério Nogueira de Souza, José Augusto Ferreira da Silva, Maria Inês Paes Ferreira   +3 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Presence of Potentially Toxic Elements in Historical Mining Areas in the North-Center of Mexico and Possible Bioremediation Strategies

Toxics
This paper provides an overview of the impacts of mining-related environmental liabilities on humans, soils, sediments, surface water and groundwater across various mining districts in Zacatecas, Mexico.
Victor Manuel Escot-Espinoza, Susana Rodríguez-Márquez, Jorge Briseño-Bugarín, Maria Argelia López-Luna, Juan Armando Flores de la Torre   +4 more
doaj   +1 more source

The Impact of Environmental Liabilities on Real Estate Contract Negotiations [PDF]

, 1990
The author examines environmental issues facing a prospective seller of industrial real property. Because a seller generally will not be able to transfer statutory responsibility for environmental problems, it is advisable for the seller to investigate ...
Karlsson, Gail V.
core   +2 more sources

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

The development of social and environmental accounting research 1995-2000 [PDF]

, 2000
This paper reviews five years of social and environmental accounting literature (from 1995-2000) in an attempt to evaluate the current position. The methodology used follows that employed in Mathews (1997a) which covered a period of 25 years in three ...
Mathews, M. R.
core  

Accurate Liability Estimation Improves Power in Ascertained Case Control Studies

, 2015
Linear mixed models (LMMs) have emerged as the method of choice for confounded genome-wide association studies. However, the performance of LMMs in non-randomly ascertained case-control studies deteriorates with increasing sample size.
AL Price, AL Price, C Lippert, C Widmer, Christoph Lippert, D Golan, D Welter, Dan Geiger, David Heckerman, DJ Balding, ER Dempster, J Listgarten, J Yang, J Yang, J Yang, LA Hindorff, LC Tsoi, M Fakiola, N Fusi, N Patterson, N Zaitlen, N Zaitlen, Omer Weissbrod, S Sawcer, S Wright, SH Lee, X Zhou   +26 more
core   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Regulatory Strategies in Environmental Liability [PDF]

, 2009
This paper analyses the possibilities of private law in remedying environmental damage. The preventive role of tort law is discussed as well as its relationship to regulation. Attention is also paid to the necessity to combine liability and regulation and to the environmental liability directive.
openaire   +2 more sources

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source