Results 131 to 140 of about 45,064 (302)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

open access: yesBMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng   +10 more
wiley   +1 more source

Strict Liability as a Deterrent in Toxic Waste Management: Empirical Evidence from Accident and Spill Data [PDF]

open access: yes
This paper explores the issue of whether strict liability imposed on polluters has served to reduce uncontrolled releases of toxics into the environment.
Austin, David, Alberini, Anna
core  

Mid‐Domain Effect and Wooded Habitat Shape Mediterranean Reptile Communities

open access: yesBiological Diversity, EarlyView.
Analyzing a large number of reptiles observed across protected areas in Central Italy, we tested whether the mid‐domain effect explains hump‐shaped richness–elevation patterns. Species richness was best predicted by the combined influence of geometric constraints and woodland cover, revealing two contrasting species clusters and offering a robust ...
Daniele Dendi   +3 more
wiley   +1 more source

Extending the role of Tort as a means of environmental protection: An investigation of recent developments of the law of Tort and the European Union

open access: yes, 1999
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The purpose of this thesis is to determine the extent to which it is possible to develop an environmental role for the law of tort.
Wilde, Mark Laurence
core  

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

open access: yesBrain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye   +14 more
wiley   +1 more source

The Corrective Tax versus Liability As Solutions to the Problem of Harmful Externalities [PDF]

open access: yes
Although the corrective tax has long been viewed by economists as a theoretically desirable remedy for the problem of harmful externalities, its actual use has been limited, mainly to the domain of pollution.
Steven Shavell
core  

Utterance evolution: the road to generative, combinatorial communicators

open access: yesBiological Reviews, EarlyView.
ABSTRACT Language has long been considered uniquely complex in the animal kingdom; however, animal research over the last decade has begun to challenge some long‐standing premises about exactly which language capacities are uniquely human. The task of resolving why and how complex communication systems evolve, particularly human language, has ...
Catherine Crockford   +2 more
wiley   +1 more source

The Equivalence of Strict Liability and Negligence Rule: A « Trompe l'œil » Perspective [PDF]

open access: yes
This paper analyzes the difficulties of comparing the respective effectiveness of two among the most important liability regimes in tort law: rule of negligence and strict liability.
Gérard Mondello
core  

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