Results 101 to 110 of about 6,902,721 (301)

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Ecological and Cost Advantage from the Implementation of Flight Simulation Training Devices for Pilot Training

open access: yesApplied Sciences
The paper discusses a case study of obtaining an airline pilot license in integrated training—the so-called “from zero to Airline Transport Pilot License”.
Marta Maciejewska   +4 more
doaj   +1 more source

De la controverse à l'acceptabilité sociale : le rôle constructif du conflit

open access: yesVertigO, 2016
We live in a context of increasing socio-economic-environmental controversies and growing demand for involvement of civil society in decision making processes related to major development projects.
Sofiane Baba, Chantale Mailhot
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Environmental Groups Treading the Discursive Tightrope of Social License: Australian and Canadian Cases Compared

open access: yesInternational Journal of Communication, 2017
Environmental nongovernmental organizations are often challenged to engage in economic debates. One response is to frame contested or protected areas and species as tourism assets.
Lyn McGaurr, Libby Lester
doaj  

Investor Protection Against Invalidity of Administrative Acts: Perspective of Decision 650 K/TUN/2022 and Investment Law

open access: yesLaw Research Review Quarterly
The issuance of mining business licenses that conflict with environmental protection regulations often leads to cancellation by the court, which directly disrupts the legal certainty of investments.
Mochammad Rizky Maulana   +2 more
doaj   +1 more source

Environmental licensing: the need for simplication

open access: yes, 2019
The licensing and the evaluation of impacts, by ensuring the knowledge and discussion by society of the socio-environmental externalities of new enterprises, are important instruments for the protection of the human rights related to populations directly and indirectly affected.
Garbaccio, Grace Ladeira   +2 more
openaire   +1 more source

The Compensation of Effectiveness Environmental as a Condition in the Process of Environmental Licensing

open access: yes, 2015
O presente trabalho, de cunho teórico, analisa principalmente o instituto da Compensação Ambiental como condicionante para o Licenciamento Ambiental. Inicialmente, abordam-se o Licenciamento Ambiental e seu modelo trifásico para concessão de licenças, perpassando pelas Licenças: Prévia, de Instalação e de Operação, citando falhas e características ...
Borges, Monike Valent Silva   +1 more
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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