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The National Environment Policy, established by Law No. 6938 of 1981, aims at environmental preservation in line with the economic and social development of the country, establishing, therefore, the appropriate guidelines and instruments. These include environmental impact assessment and environmental licensing of effective or potentially potentially ...
Mello, Marcela Souza Zarske de +1 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The Department of Chocó is a “territory with an incalculable natural, ethnic and cultural wealth” (¿Qué es él Chocó Biogeográfico?, 2013); Prior consultation is a right and a mechanism involving ethnic groups, however, is not effective, or is an ...
Marisela Mena Valencia +1 more
doaj
Teen driver's attitudes, knowledge and motor vehicle violations in relationship to Wisconsin's Graduated License law [PDF]
Plan BThe purpose of this research was to determine the extent that restrictions imposed by the Wisconsin Graduated Licensing system are being followed by Polk and Burnett County teenage drivers. As a result of present data which indicates that Wisconsin’
Erickson, Wade J.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Policy Development for Environmental Licensing and Biodiversity Offsets in Latin America
Attempts to meet biodiversity goals through application of the mitigation hierarchy have gained wide traction globally with increased development of public policy, lending standards, and corporate practices. With interest in biodiversity offsets increasing in Latin America, we seek to strengthen the basis for policy development through a review of ...
Villarroya-Ballarín, A. (Ana) +2 more
openaire +5 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The research aims to discover the relation between debureaucratization of licensing service and actualization of license function as a control to society’s threatening activities in order to avoid vicinity’s threats. The research resulted in some points,
Nurwigati Nurwigati
doaj

