Results 51 to 60 of about 6,259 (258)

Source-to-sink magnetic properties of NE Saharan dust in Eastern Mediterranean marine sediments: a review and paleoenvironmental implications

open access: yesFrontiers in Earth Science, 2015
We present a review of the magnetic properties of NE Saharan dust that was conducted, following a source-to-sink approach, to unravel the paleoclimatic significance of environmental magnetic records from Eastern Mediterranean marine sediments.
Juan Cruz Larrasoaña
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Subducted oceanic crust as the origin of seismically slow lower-mantle structures

open access: yesProgress in Earth and Planetary Science, 2020
Mantle tomography reveals the existence of two large low-shear-velocity provinces (LLSVPs) at the base of the mantle. We examine here the hypothesis that they are piles of oceanic crust that have steadily accumulated and warmed over billions of years. We
Timothy D. Jones   +4 more
doaj   +1 more source

Benefits and Limitations of Environmental Magnetism for Completing Citizen Science on Air Quality: A Case Study in a Street Canyon

open access: yesCommunity Science, 2023
This paper details the operating experience about a case study carried out as a citizen science approach to monitor magnetic particulate matter (PM) in a street canyon in Montpellier, France.
S. Letaïef   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Magnetic properties of cherts from the Basque-Cantabrian basin and surrounding regions: archeological implications

open access: yesFrontiers in Earth Science, 2016
We present the first rock magnetic study of archeologically-relevant chert samples from the Basque-Cantabrian basin (BCB) and surrounding regions, which was conducted in order to test the usefulness of non-destructive magnetic properties for assessing ...
Juan Cruz Larrasoaña   +6 more
doaj   +1 more source

An Attempt to Recover a Paleomonsoon Signal in the Chinese Loess Plateau Using Anisotropy of Magnetic Susceptibility

open access: yesFrontiers in Earth Science, 2020
The paleowind direction in the Chinese Loess Plateau (CLP) was studied using anisotropy of magnetic susceptibility (AMS) data. Magnetic fabrics were examined for the last glacial loess (L1) and last inter-glacial paleosol (S1) in the southern and central
Feng Xian   +5 more
doaj   +1 more source

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