Results 41 to 50 of about 4,189,438 (285)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

VDMS: An Improved Vision Transformer-Based Model for PM_2.5 Concentration Prediction

Applied Sciences
China’s accelerating industrialization has led to worsening air pollution, characterized by recurrent haze episodes. The accurate quantification of PM2.5 distribution is crucial for air quality assessment and public health management.
Tong Zhao, Meixia Qu
doaj   +1 more source

Weaving Indigenous knowledge systems and Western sciences in terrestrial research, monitoring and management in Canada: A protocol for a systematic map

Ecological Solutions and Evidence, 2021
Human activities and development have contributed to declines in biodiversity across the globe. Understanding and addressing biodiversity loss will require the mobilization of diverse knowledge systems.
Dominique A. Henri, Jennifer F. Provencher, Ella Bowles, Jessica J. Taylor, Jade Steel, Carmen Chelick, Jesse N. Popp, Steven J. Cooke, Trina Rytwinski, Deborah McGregor, Adam T. Ford, Steven M. Alexander   +11 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Implementation of the Environmental Management Concept in the Hospitality Industry

Scientific Papers Animal Science and Biotechnologies, 2023
Globally, the concern for the environment is continually growing, among travel and tourism industry operators. Each unit hotel has its identity, its characteristics, and therefore, it is necessary to use and apply specific information about the ...
Manuela-Dora Orboi, Adrian Băneş, Sorin Stanciu, Tiberiu Iancu   +3 more
doaj  

Environmental Response Management Application [PDF]

, 2008
The Coastal Response Research Center (CRRC), a partnership between the University of New Hampshire (UNH) and NOAA\u27s Office of Response and Restoration (ORR), is leading an effort to develop a data platform capable of interfacing both static and real ...
Braswell, Rob, Jacobi, Michele, Kinner, Nancy E, Merten, Amy A, Newman, Kimberly S, Schwehr, Kurt   +5 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Environmental laws elicit evolution in pest management

California Agriculture, 2005
California Agriculture - All ...
R Van Steenwyk, F Zalom
doaj