Results 51 to 60 of about 14,719,621 (388)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

SELF-PROMOTION OF THE MONOGRAPH "OUTLINE OF THE THEORY OF THE STATE AS AN ECOLOGICALLY SAFE ORGANIZATION IN EMPIRICAL RESEARCH"

Humanities and Social Sciences
Four concepts – ecological security, social responsibility, sustainable development, and environmental management – are analyzed to show that the same terminology can represent different meanings and approaches to the development of a state or urban ...
Ewa Jadwiga LIPIŃSKA
doaj   +1 more source

Implementation of the Environmental Management Concept in the Hospitality Industry

Scientific Papers Animal Science and Biotechnologies, 2023
Globally, the concern for the environment is continually growing, among travel and tourism industry operators. Each unit hotel has its identity, its characteristics, and therefore, it is necessary to use and apply specific information about the ...
Manuela-Dora Orboi, Adrian Băneş, Sorin Stanciu, Tiberiu Iancu   +3 more
doaj  

How digital transformation improves corporate environmental management: A review and research agenda [PDF]

, 2022
Jiahui Xia, Zhanchi Wu, Binhai Chen
openalex   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Growth and Diet of Northern Pike (Esox lucius) in Boreal Lakes: Implications for Ecosystem Management

Hydrobiology
An important top-down predator, the northern pike (Esox lucius), faces harsh environmental conditions in the northern boreal ecoregion. They are often managed for recreational fishing and, more recently, to create environmental offsets; strategies aimed ...
Sebastian Theis, Jesse Shirton, Michael Barbeau, Jonathan L. W. Ruppert, Mark S. Poesch   +4 more
doaj   +1 more source

Penerapan Sanksi Administrasi Pencemaran Lingkungan Hidup Akibat Kegiatan Industri (Studi Kasus Di CV. Slamet Widodo di Semarang)

Unnes Law Journal, 2015
Kota Semarang sebagai kota industri dihadapi berbagai masalah pencemaran lingkungan. CV. Slamet Widodo bergerak di bidang pengolahan dan pembuatan terasi. Dalam prosesnya bau terasi tersebut mengakibatkan bau terasi yang begitu menyengat.
Harry Agung Ariefianto
doaj   +1 more source

Weaving Indigenous knowledge systems and Western sciences in terrestrial research, monitoring and management in Canada: A protocol for a systematic map

Ecological Solutions and Evidence, 2021
Human activities and development have contributed to declines in biodiversity across the globe. Understanding and addressing biodiversity loss will require the mobilization of diverse knowledge systems.
Dominique A. Henri, Jennifer F. Provencher, Ella Bowles, Jessica J. Taylor, Jade Steel, Carmen Chelick, Jesse N. Popp, Steven J. Cooke, Trina Rytwinski, Deborah McGregor, Adam T. Ford, Steven M. Alexander   +11 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source