Results 71 to 80 of about 14,869,790 (384)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

MUNICIPAL SOLID WASTE MANAGEMENT IN THE AMAZON: ENVIRONMENTAL, SOCIAL, AND ECONOMIC PROBLEMS, GAPS, AND CHALLENGES [PDF]

, 2020
Benone Otávio Souza de Oliveira, Gerson Araújo de Medeiros   +1 more
openalex   +1 more source

Stakeholder perceptions of the benefits and barriers of implementing environmental management systems in the Nigerian construction industry

Journal of Environmental Engineering and Landscape Management, 2016
This study investigates stakeholder opinions of the major benefits and barriers of Environmental Management Systems (EMS) to the Nigerian construction industry, and the perceived issues to EMS adoption among organisations in the industry.
Victoria O. Owolana, Colin A. Booth
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Environmental Law, Governance, and Management- the Need for Environmental Management Systems for Cities [PDF]

, 2012
Human activities damage the environment. They deplete natural resources, generate pollution and wastes, accelerate the loss of forests and biological diversity, as well as threaten the water supply. As populations increase, these problems are exacerbated.
Lin Heng, Lye
core   +1 more source

Benefits in environment-related measures for company due to EMS implementation [PDF]

, 2020
In the urban development, Environmental Management System (EMS) is known as a standardization of working system that thoroughly considered environmental improvement by the management of environmental data and information in the company. In line with that,
Abdul Kadir, Muhamad Nazmie, Abdulmottaleb Elgadi, Ahmed, Alias, Mohamad Fakhrul Zahin, Ku Samsu, Ku Noor Syazana, Lau, Hau Yee   +4 more
core  

Solid waste management trends in Nigeria [PDF]

, 2016
<p>The purpose of this paper is to investigate the current trend of solid waste management in Nigeria and to identify the major challenges inhibiting the attainment of sustainable solid waste management in the country. The study relied on a desktop
Amasuomo, Ebikapade, Baird, Jim
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Ideal integrated national environmental management system for South Africa : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies at Massey University [PDF]

, 1995
The South African environmental management system has been characterised by fragmentation and the lack of effective legislation. The number of statutes concerned with conservation issues is an associated problem.
Utlwa, Abel Pheello
core