RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
An empirical study of environmental cost drivers [PDF]
This paper draws on Environmental Management Accounting (EMA) literature and cost driver theory to study the nature and role of environmental cost drivers.
Benjamin Dreveton +3 more
core +3 more sources
ENVIRONMENTAL-ECONOMIC ACCOUNTING AND ASSESS THE EFFECTIVENESS OF ENVIRONMENTAL MANAGEMENT
The article discusses the reflection of natural assets in national accounts meso- and megaeconomic level. The peculiarities of valuation of natural assets as a complex ecological-economic categories, which should be oriented not on the market, and the ...
Anatoly Belousov, Lilia Blizno
doaj
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Pengaruh Strategi Bisnis dan Ketidakpastian Lingkungan terhadap Kualitas Sistem Informasi Akuntansi Manajemen (Studi pada PT. Pos Indonesia Bandung) [PDF]
Business strategy and environmental uncertainty are popular and complex concepts that are identified as factors that can affect the quality of management accounting information systems.
Hidayat, I. F. (Indriani)
core
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Integration of the Pro-Environmental Concepts in Various Management Accounting Tools
Integrating pro-environmental concepts into management accounting tools is essential for organizations aiming to enhance their sustainability performance. Measures to support a pro-environmental attitude in each enterprise can be implemented differently.
Anna SIEMIONEK-LEPCZYŃSKA +1 more
doaj +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Pengaruh Strategi Bisnis dan Ketidakpastian Lingkungan terhadap Kualitas Sistem Informasi Akuntansi Manajemen (Studi pada PT Lestari Mahaputra Buana) [PDF]
Business Strategy is a set of plans and integrated action which is designed for the company As a means to gain profit beyond its competitors As well as to maximize profit.
Muslimatunisa, A. (Arti)
core

