We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Estimation of SPAD values in litchi based on improved LSTM with fusion of IoT and multispectral image texture features. [PDF]
Li Z, Chen X, He J, Chen L, Gao P.
europepmc +1 more source
An architecture‐enabled bottom‐heated 3D solar convective evaporator spatially decouples photothermal heating from evaporation, triggering natural convection that intensifies sidewall vapour removal and heat transfer. The system achieves significantly enhanced evaporation rates over 2D and conventional 3D designs while confining salt precipitation to ...
Xiaolong Ma +7 more
wiley +1 more source
Environmental footprint of peritoneal dialysis in Europe: a comparative life cycle assessment across four European centres. [PDF]
Fehintola A +21 more
europepmc +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
How the proposal for a new regulation for new genomic techniques affects the European Union's food system sustainability objectives. [PDF]
Kardung M +11 more
europepmc +1 more source
Conformal Metallosaccharide Hybrid Films for Protecting Wood Surfaces From Environmental Damage
Ti‐ribose hybrid films fabricated by molecular layer deposition form a conformal and uniform coating on wood surfaces, which provides water repellence, dimensional stability, and resistance to acidic and alkaline environments, while preserving the natural appearance.
Wenwen Wang +7 more
wiley +1 more source
Urban Waste Management, Air Quality, and Public Health: Assessing the Health Burden of Rapid Urbanization in Sub-Saharan Africa. [PDF]
John C.
europepmc +1 more source
Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries
A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy +5 more
wiley +1 more source

