Results 71 to 80 of about 609,076 (254)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Research on Countermeasures to Build a Green University Management System under the Concept of Ecological Education

open access: yesProblemy Ekorozwoju
Higher learning institutions have played a significant role in enhancing ecological education and ideological development among students. This is in response to the many problems occurring in the modern world concerning ideological and environmental ...
Jing Zhou
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

The Effectiveness of Environmental Management in a Metallurgical Company’s Sustainable Development

open access: yesMetalurgija, 2010
In the article metallurgy enterprises are being characterised, taking into account, in particular, the environmental management systems as well as the effects of their introduction, on the example of Ferrum SA.
R. Wieszała, B. Gajdzik
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

ANALISA SISTEM MANAJEMEN LINGKUNGAN ISO 14000 DAN KEMUNGKINAN IMPLEMENTASINYA OLEH PARA KONTRAKTOR KELAS A DI SURABAYA

open access: yesCivil Engineering Dimension, 2002
Sustainable construction development needs a good environmental management system. International standard ISO 14000 is one the standard of a good environmental management system. This research aims to obtain general idea on how far Class A contractors in
Herry Pintardi Chandra
doaj  

Les comportements écologiques des dirigeants des entreprises tunisiennes

open access: yesVertigO, 2009
In 1988, some Tunisian firms, essentially in reaction with the environmental regulation, have instituted environmental initiatives. The objective of this research is to classify the Tunisian managers based on their environmental commitment.
Ahmed Turki
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

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