Results 41 to 50 of about 561,985 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ENVIRONMENTAL MANAGEMENT SYSTEMS CERTIFICATION

open access: yesJournal of Economic Development, Environment and People, 2012
ISO 14001 prescribes the requirements for a system, not environmental performance itself. Similarly, certification is of the management system itself, not environmental performance.
Aniko Miler-Virc, Zdravko Glusica
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Environmental management control systems for carbon emissions [PDF]

open access: yesPSU Research Review, 2017
Purpose – This paper aims to focus on a global consulting company and examine how it struggled to establish an effective environmental management control system for carbon emissions for its employees’ air travel.
Nadia Di Giacomo   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Woodland expansion and deer management shape tick abundance and Lyme disease hazard

open access: yesEcological Solutions and Evidence
The largest land use change in Europe is woodland expansion, through planting and natural regeneration. Unforeseen consequences of this could include changes in environmental hazards, such as exposure to parasites and pathogens.
Fanny Olsthoorn   +10 more
doaj   +1 more source

Rolul sistemelor de management de mediu voluntare în cadrul politicii de mediu. Perspectiva managerilor companiilor private

open access: yesRevista Transilvană de Ştiinţe Administrative, 2020
The present article is part of a wider investigation of private environmental management systems, conducted as part of the doctoral research. The perspective of the private sector managers on the role of the voluntary management systems was left ...
Raluca Suciu
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Environmental management systems [PDF]

open access: yes, 2016
This book has been published under the project „The creation of new interdisciplinary curricula in the field of economics of environmental protection (in Polish and English) at the University of Łódź” supported by a grant from Norway through the Norway Grants and co-financed by the Polish funds. (Agreement No FSS/2014/HEI/W/0124/U/0014).
openaire   +4 more sources

Designing a suite of measurements to understand the critical zone [PDF]

open access: yesEarth Surface Dynamics, 2016
Many scientists have begun to refer to the earth surface environment from the upper canopy to the depths of bedrock as the critical zone (CZ). Identification of the CZ as an integral object worthy of study implicitly posits that the study of the whole ...
S. L. Brantley   +14 more
doaj   +1 more source

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