Results 81 to 90 of about 448,805 (255)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems

Scientific Reports
Antimicrobial resistance (AMR) is a global health challenge requiring cross-sector action, with research largely focused on chickens, leaving ducks underexplored.
Zsombor Szoke, Peter Fauszt, Maja Mikolas, Peter David, Emese Szilagyi-Tolnai, Georgina Pesti-Asboth, Judit Rita Homoki, Ildiko Kovacs-Forgacs, Ferenc Gal, Laszlo Stundl, Levente Czegledi, Aniko Stagel, Sandor Biro, Judit Remenyik, Melinda Paholcsek   +14 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Environmental Management Systems and Sustainability in SMEs

MATEC Web of Conferences, 2016
Environmental sustainability in manufacturing sector has been allocated a major consideration in the international literature. Due to growing concerns over the high effect of SMEs on world manufacturing industries and their contribution to pollution ...
Shah Satya, Ganji Elmira, Hasan Syed
doaj   +1 more source

EXPERIMENTAL VERIFICATION OF THE STRUCTURAL AND TECHNOLOGICAL PARAMETERS OF THE PKS

Acta Polytechnica, 2014
This paper presents the theoretical design for experimental verification of the structural and technological parameters of the Parallel Kinematic Structure.
Iveta Onderová, Ludovít Kolláth, Lucia Ploskuňáková   +2 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

LIFE CYCLE ASSESSMENT OF ARUNDO DONAX BIOMASS PRODUCTION IN A MEDITERRANEAN EXPERIMENTAL FIELD USING TREATED WASTEWATER

Journal of Agricultural Engineering, 2012
In this study the Life Cycle Assessment (LCA) of the Arundo donax production process for energy purpose is proposed. The cultivation of this type of herbaceous biomass, irrigated with urban wastewater, was carried out in an experimental field, sited in ...
Claudia Arcidiacono, Simona M.C. Porto
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

IMPROVING PER-PIXEL CLASSIFICATION OF CROP-SHELTER COVERAGE BY TEXTURE ANALYSES OF HIGH-RESOLUTION SATELLITE PANCHROMATIC IMAGES

Journal of Agricultural Engineering, 2012
Actual research challenges in automated recognition of crop shelters regard, among other issues, the accuracy of classification, contour detection and typology identification.
Claudia Arcidiacono, Simona M.C. Porto
doaj   +1 more source