Results 121 to 130 of about 1,142,885 (215)

[Environmental medicine and AI, migration, and emerging and reemerging diseases in Mexico]. [PDF]

Rev Med Inst Mex Seguro Soc
Rivera-Silva G, Moreno-Treviño MG, Garza-Martínez R.   +2 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Occurrence and hygienic/allergological relevance of mould from point of view of the environmental medicine. [PDF]

Allergol Select, 2018
Gabrio T, Weidner U.
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Project ECHO Occupational and Environmental Medicine: A Qualitative Study of HealthCare Providers Supporting Workers with Work-Related Injuries and Illnesses. [PDF]

J Occup Rehabil
Nowrouzi-Kia B, Carlin L, Furlan AD, Harbin S, Severin CN, Irvin E, Carnide N, Thompson AMS, Adisesh A.   +8 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Medicine versus environmental manipulations as approaches to treating dry eye disease: why does medicine usually win?

BMJ Open Ophthalmology, 2023
Anat Galor, Naresh Kumar, Kimberly Cabrera, Ana M Palacio   +3 more
doaj   +1 more source

Inclusion of Drinking Water Source and Testing Questions into Electronic Medical Records: Advancing Environmental Medicine and Public Health Outreach in New Jersey. [PDF]

J Public Health Manag Pract
Flanagan SV, Braman S, Puelle R, Gleason JA, Spayd SE, Navas-Acien A, Chillrud S.   +6 more
europepmc   +1 more source