Results 111 to 120 of about 692,387 (280)

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Monodeuterated Methane, an Isotopic Tool To Assess Biological Methane Metabolism Rates

open access: yesmSphere, 2017
Biological methane oxidation is a globally relevant process that mediates the flux of an important greenhouse gas through both aerobic and anaerobic metabolic pathways.
Jeffrey J. Marlow   +6 more
doaj   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu   +6 more
wiley   +1 more source

Functional and Comparative Genomic Analysis of Integrated Prophage-Like Sequences in “Candidatus Liberibacter asiaticus”

open access: yesmSphere, 2019
Huanglongbing disease (HLB; yellow shoot disease) is a severe worldwide infectious disease for citrus family plants. The pathogen “Candidatus Liberibacter asiaticus” is an alphaproteobacterium of the Rhizobiaceae family that has been identified as the ...
Marian Dominguez-Mirazo   +2 more
doaj   +1 more source

Bacteriological and epidemiological studies of campylobacter spp. in Swedish broilers [PDF]

open access: yes, 2007
Campylobacter jejuni is the most frequently reported cause of bacterial gastrointestinal illness in humans in Sweden. Chicken products are considered an important risk factor for human infection.
Hansson, Ingrid
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Bacttle: a microbiology educational board game for lay public and schools

open access: yesJournal of Microbiology & Biology Education
Inspired by the positive impact of serious games on science understanding and motivated by personal interests in scientific outreach, we developed “Bacttle,” an easy-to-play microbiology board game with adaptive difficulty, targeting any player from 7 ...
Tania Miguel Trabajo   +2 more
doaj   +1 more source

The Impact of DNA Polymerase and Number of Rounds of Amplification in PCR on 16S rRNA Gene Sequence Data

open access: yesmSphere, 2019
PCR amplification of 16S rRNA genes is a critical yet underappreciated step in the generation of sequence data to describe the taxonomic composition of microbial communities. Numerous factors in the design of PCR can impact the sequencing error rate, the
Marc A. Sze, Patrick D. Schloss
doaj   +1 more source

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