Results 111 to 120 of about 4,880,581 (325)

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Exploring Trichoderma Species in Industrial Wastewater: Morphological and Molecular Insights from Isolates

Life
The genus Trichoderma holds economic significance due to its widespread distribution and diverse applications, including biological control, enzyme production, and various biotechnological uses.
Syeda Bint-e-Zahira, Abdul Nasir Khalid, Nousheen Yousaf, Muhammad Iqbal, Tauseef Anwar, Huma Qureshi, Saleh H. Salmen, Mohammad Javed Ansari   +7 more
doaj   +1 more source

Trends in Microbiology 2024

Microbiology is a key component of modern science, significantly influencing various fields, such as agriculture, medicine, and environmental management, particularly through the One Health approach, which recognizes the interconnectedness of human ...
Pabulo Henrique Rampelotto, Milan Kolář   +1 more
core   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Adaptation of clinical bacteriology techniques for remote polar research

Remote polar regions offer unique opportunities and significant challenges for antimicrobial resistance research in a near-pristine environment. While core microbiology techniques continue to have an important role in supporting environmental research ...
Pallett, Scott JC, Wong, Stephanie MY, Kwok, Bill K, Moore, Luke SP   +3 more
core   +1 more source

The environmental microbiology of melioidosis

Reviews in Medical Microbiology, 2001
Melioidosis is an unusual bacterial infection. While on the one hand melioidosis can present as an acute, rapidly fatal septicaemia, the causative agent, Burkholderia pseudomallei, can also cause localised soft tissue infection or seroconversion without clinically evident infection.
Timothy J. J. Inglis, Brian J. Mee, Barbara J. Chang   +2 more
openaire   +2 more sources

Application of phenotypic microarrays to environmental microbiology.

Current Opinion in Biotechnology, 2012
Environmental organisms are extremely diverse and only a small fraction has been successfully cultured in the laboratory. Culture in micro wells provides a method for rapid screening of a wide variety of growth conditions and commercially available ...
S. Borglin, D. Joyner, K. DeAngelis, J. Khudyakov, P. D’haeseleer, marcin p. joachimiak, T. Hazen   +6 more
semanticscholar   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

The urgent need for microbiology literacy in society.

Environmental Microbiology, 2019
Microbes and their activities have pervasive, remarkably profound and generally positive effects on the functioning, and thus health and well-being, of human beings, the whole of the biological world, and indeed the entire surface of the planet and its ...
K. Timmis, R. Cavicchioli, J. L. García, B. Nogales, M. Chavarría, L. Stein, T. McGenity, N. Webster, B. Singh, J. Handelsman, V. Lorenzo, C. Pruzzo, J. Timmis, Juan Luis Ramos Martín, W. Verstraete, M. Jetten, A. Danchin, Wei E. Huang, J. Gilbert, R. Lal, H. Santos, Sang Yup Lee, A. Sessitsch, P. Bonfante, L. Gram, Raymond Lin, E. Ron, Z. Karahan, Jan Roelof Meer, Seza Artunkal, D. Jahn, Lucy Harper   +31 more
semanticscholar   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source