Results 101 to 110 of about 7,856,330 (296)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2019 Eriocheir leptognathus is a dominant species in the Yangtze River estuary. In this study, we first determined the complete mitochondrial genome (mitogenome) of E. leptognathus. The mitogenome is 16,143 bp in length, consisting of 13 protein-coding genes (
YiMing Yuan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
A decade-long perspective on marine health changes in Dalian, China
Frontiers in Marine ScienceThe ocean, serving as the cradle of life on Earth and the regulator of global climate, constitutes an invaluable resource repository for human survival and development.
Xiaocheng Wang +6 more
doaj +1 more source
The complete mitochondrial genome of Exopalaemon annandalei
Mitochondrial DNA. Part B. Resources, 2018 In this study, the complete mitochondrial genome (mitogenome) of Exopalaemon annandalei was amplified and analyzed. The mitogenome is 15,718 bp in length, encoding 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes, and a control region (CR ...
YiMing Yuan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Study on the Stability Evaluation of Sand Bar-lagoon Geomorphology System in Fudu River Estuary
Haiyang Kaifa yu guanli, 2022 Sand bar-lagoon is a kind of geomorphic system which is in the process of dynamic equilibrium adjustment. It has typical estuarine ecosystem and important scientific research value.
Pan ZHANG +5 more
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
, 2020 In this article, the authors apply the relative air pollution index (RAPI) proposed by Pham Ngoc Ho for aggregate assessment of daily air pollution level (RAPId) using data from 3 daily standards (1, 8, and 24 h) of each country’s standard, including ...
Do D.M. +4 more
core +1 more source
Haiyang Kaifa yu guanliMarine geoengineering has garnered considerable attention as a promising avenue for climate change mitigation. Within its two principal branches, research on marine carbon dioxide removal (CDR) has demonstrated substantial progress as demonstrated by a ...
WEI Shuyun +5 more
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