Results 111 to 120 of about 890,558 (368)

Evaluating the ecological realism of plant species distribution models with ecological indicator values [PDF]

open access: yes, 2020
Species distribution models (SDMs) are routinely applied to assess current as well as future species distributions, for example to assess impacts of future environmental change on biodiversity or to underpin conservation planning.
Ellenberg H.   +16 more
core   +1 more source

Niche Modeling of Dengue Fever Using Remotely Sensed Environmental Factors and BRT

open access: yesOnline Journal of Public Health Informatics, 2018
ObjectiveIn this paper we used Boosted Regression Tree analysis coupled with environmental factors gathered from satellite data, such as temperature, elevation, and precipitation, to model the niche of Dengue Fever (DF) in Colombia.IntroductionDengue Fever (DF) is a vector-borne disease of the flavivirus family carried by the Aedes aegypti mosquito ...
Ashby, Jeffrey L.   +1 more
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Experimental validation of multiphase flow models and testing of multiphase flow meters: A critical review of flow loops worldwide [PDF]

open access: yes, 2016
Around the world, research into multiphase flow is performed by scientists with hugely diverse backgrounds: physicists, mathematicians and engineers from mechanical, nuclear, chemical, civil, petroleum, environmental and aerospace disciplines ...
Bello, O. O.   +2 more
core   +1 more source

Can Ecological Interactions be Inferred from Spatial Data? [PDF]

open access: yes, 2020
The characterisation and quantication of ecological interactions, and the construction of species distributions and their associated ecological niches, is of fundamental theoretical and practical importance.
Gonzalez-Salazar, Constantino   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Populus tremuloides seedling establishment: An underexplored vector for forest type conversion after multiple disturbances [PDF]

open access: yes, 2017
Ecosystem resilience to climate change is contingent on post-disturbance plant regeneration. Sparse gymnosperm regeneration has been documented in subalpine forests following recent wildfires and compounded disturbances, both of which are increasing.
Buma, Brian   +3 more
core   +1 more source

Web-based interface for environmental niche modelling

open access: yes, 2021
Marine species are subject to anthropogenic impacts, such as noise pollution, marine litter, and direct impact collisions. While there are efforts in the marine community and crowd-sourcing to report the occurrence of marine species, not enough projects explore the prediction of where such animals may be. This dissertation analyzes the state of the art
openaire   +1 more source

Niche Modeling of Dengue Fever Using Remotely Sensed Environmental Factors and Boosted Regression Trees [PDF]

open access: yesRemote Sensing, 2017
Dengue fever (DF), a vector-borne flavivirus, is endemic to the tropical countries of the world with nearly 400 million people becoming infected each year and roughly one-third of the world’s population living in areas of risk. The main vector for DF is the Aedes aegypti mosquito, which is also the same vector of yellow fever, chikungunya, and Zika ...
Jeffrey Ashby   +3 more
openaire   +1 more source

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