Results 121 to 130 of about 890,558 (368)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Utilizing ecological niche modelling to predict habitat suitability of eastern equine encephalitis in Florida

Annals of GIS, 2020
Eastern Equine Encephalitis virus (EEEV) is a virus found predominantly east of the Mississippi River in the United States that can be fatal to both equines and humans.
Claire Burch, Rebecca Loraamm, Thomas Unnasch, Joni Downs   +3 more
doaj   +1 more source

The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock and wildlife. [PDF]

, 2019
Bacillus anthracis is a spore-forming, Gram-positive bacterium responsible for anthrax, an acute infection that most significantly affects grazing livestock and wild ungulates, but also poses a threat to human health.
Alexander, Kathleen A, Bagirova, Mehriban, Blackburn, Jason K, Carlson, Colin J, Elkin, Brett T, Epp, Tasha, Fegan, Mark, Getz, Wayne M, Hugh-Jones, Martin E, Kracalik, Ian T, Ross, Noam, Shury, Todd K, Zhang, Wenyi   +12 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Spatial and Temporal Distribution Pattern of Oncomelania hupensis Caused by Multiple Environmental Factors Using Ecological Niche Models [PDF]

, 2022
Qianwen Shi, Yanfeng Gong, Jian Zhao, Zhiqiang Qin, Jun Zhang, Jingzhi Wu, Zengyun Hu, Shi‐Zhu Li   +7 more
openalex   +1 more source

Ecological and geographical considerations on environmental niche modelling

, 2019
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Da Re, Daniele, Cornejo Rubin De Celis, Sergio Steven, Vanwambeke, Sophie, Belgian Geographers days 2019   +3 more
openaire   +3 more sources

Open-source software integration: A tutorial on species distribution mapping and ecological niche modelling [PDF]

Research Ideas and Outcomes
Over the last decade, access to global data has become increasingly critical for research, allowing insights into diverse biological, environmental and societal questions at a macro scale.
Zoe Ryan, Emily Clark, Beatrice Cundiff, Joslyn Nichols, Maya Mahoney, Nkosi Evans, Thomas Campbell, Danny Kreider, Matt von Konrat   +8 more
doaj   +3 more sources

Genome-wide admixture and ecological niche modelling reveal the maintenance of species boundaries despite long history of interspecific gene flow

Molecular Ecology, 2014
The maintenance of species boundaries despite interspecific gene flow has been a continuous source of interest in evolutionary biology. Many hybridizing species have porous genomes with regions impermeable to introgression, conferring reproductive ...
Amanda R. De La Torre, D. Roberts, S. Aitken   +2 more
semanticscholar   +1 more source