Results 121 to 130 of about 3,729,294 (289)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Carbon Emission Disclosure and Its Impact on Developing Countries
Jurnal Ilmu LingkunganThis study aims to explore carbon emission disclosure practices in Indonesia, and extensive testing by providing one representative variable for each group of factors thought to be influential.
Indah Fajarini Sri Wahyuningrum +6 more
doaj +1 more source
Environmental policy as a multi-task principal-agent problem [PDF]
We use a multi-task principal-agent model with moral hazard to study environmental regulation of a private agent by an EPA that can also allocate its budget to an alternative project with environmental benefits.
Alessio D'Amato, Laurent Franckx
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IT Innovativeness and Environmental Consciousness on Organizational Performance [PDF]
The purpose of our study is to investigate the impacts of Information Technology (IT) innovation and environmental consciousness on firm performance. We tested the robustness of innovation theory using the most recent Information Week (IW) 500 annual ...
Myung Ko
core
Top management team and board attributes and firm performance in the Netherlands [PDF]
, 1999 We survey the evidence on the relationship between board and top management team attributes and firm performance in the Netherlands (sample of 94 listed firms).
Ees, Hans van, +2 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Frontiers in Environmental ScienceThis study investigates the impact of green technology (GT), energy intensity (EIN), environmental performance (EPR), and economic growth (GDP) on carbon emissions (CEM) across the G5 economies—Brazil, China, India, Mexico, and South Africa—over the ...
Qingdong Hao, Rimsha Arshad
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source