Results 71 to 80 of about 1,213,044 (313)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Corporate Environmental Performance: Consistency of Metrics and Identification of Drivers [PDF]

open access: yes
This study is among the first to provide insight into the assessment of the convergent validity of widely used environmental performance ratings. Using a set of environmental dimensions in KLD, GES, and ASSET4 ratings, this study demonstrates that the ...
Semenova, Natalia
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Flywheel Resistance Training for Anterior Cruciate Ligament Rehabilitation

open access: yesInternational Journal of Strength and Conditioning
The tearing or rupturing of the anterior cruciate ligament (ACL) has become an increasingly common injury in athletes, particularly in sports that require sharp, pivoting movements and sports that have high deceleration and landing demands.
Margaret Michalak   +3 more
doaj   +1 more source

ANALISIS PENGARUH KINERJA LINGKUNGAN TERHADAP KINERJA INDUSTRI KECIL

open access: yesJurnal Dinamika Manajemen, 2012
Tujuan penelitian adalah mengidentifikasi, menganalisis praktik pengelolaan lingkungan pada sentra industri kecil dibandingkan best practices dalam upaya meningkatkan kinerja lingkungan di Kabupaten Pati.
Sukirman -
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Characterising performance of environmental models

open access: yesEnvironmental Modelling & Software, 2013
In order to use environmental models effectively for management and decision-making, it is vital to establish an appropriate level of confidence in their performance. This paper reviews techniques available across various fields for characterising the performance of environmental models with focus on numerical, graphical and qualitative methods ...
Neil D. Bennett   +15 more
openaire   +6 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

The impact of voluntary environmental protection instruments on company environmental performance

open access: yes, 2004
In the last decade there has been increasing emphasis on the use of voluntary environmental protection tools such as corporate environmental reporting (CER) and environmental management systems (EMSs).
David Annandale   +5 more
core   +2 more sources

The Effect of Lightweight Wearable Resistance on the Squat and Countermovement Jumps: Does Load Dampen the Performance-Enhancing Effect of the Stretch-Shortening Cycle?

open access: yesApplied Sciences
This study investigated the effects of lightweight wearable resistance on the kinetics and kinematics of squat jumps (SJ) and countermovement jumps (CMJ) with 2%, 4%, and 6% body mass (BM). Twenty male athletes (age: 18.05 ± 0.6 years; weight: 76.4 ± 7.6
Hamish Kyne, John B. Cronin
doaj   +1 more source

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